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Light Microscopy

The Light Microscopy Core Technology Platform provides access to several state-of-the-art microscopes and aids in the following research activities:

Confocal and super-resolution imaging:
The microscopy facility applications include molecular motor transport studies, 3D neuronal network imaging and nanoparticle testing and cell screening. The facility also can perform imaging of fluorescently labeled samples including drosophila brains, mouse brain sections and cultured cells.

Widefield microscopy:
Various imaging techniques are used in widefield microscopy which include epifluorescence, phase contract, and differential contrast microscopy. These are used in the core facility in various projects such as cell growth and proliferation regulation studies, actin reprogramming and C. elegans embryogenesis.

Sample preparation:
The facility supports researchers in experimental design and suggests different labeling techniques and microscopes setups for the various applications.

Data Analysis:
Various software programs are available for the post processing of the images on a processing workstation (Autoquant, Imaris, Matlab, LasX offline license).

Equipment List

  • Biotek Instrument- LionHeart LLX
  • Confocal Microscope - Leica SP8
  • Confocal Two-Photon Microscope (Inverted) - Olympus FV1000
  • Confocal Two-Photon Microscope (Upright) - Olympus FV1000
  • Evident FV4000 MPE Two-Photon Microscope
  • EVOS FL Auto Imaging System 
  • EVOS FL Cell Imaging System 
  • Kibero easySAM Acoustic and Photoacoustic Microscope
  • Holographic Microscope - Nanolive 3D Cell Explorer
  • Leica Stellaris 8 Confocal Microscope
  • Metallurgical Microscope - Nikon LV-Dia
  • Microscopy Processing Station II - SuperMicro
  • Nikon LV100 DIC/Flurorescence Metallurgical Microscope 
  • Nikon SMZ18 Stereomicroscope 
  • Primo - Micropatterning system
  • Stereo Microscope - Leica M205C
  • Super Resolution Microscope - Leica STED 3X
  • Thorlab Ganymede GAN611 - Optical Coherence Tomography Microscope
  • Widefield Microscope - Leica DMI3000
  • Widefield Microscope - Leica DMI6000
  • Widefield Microscope - Olympus IX83