High-Throughput Screening

The High-Throughput Screening (HTS) Core Technology Platform, managed by the Center of Genomics and Systems Biology team, allows researchers to rapidly automate thousands of chemical and biological assays. It is used by biologists and chemists to screen large libraries of chemical and biological reagents for bioactive compound discovery, toxicity studies, and cell biology research.

This CTP is equipped with an integrated screening platform and advanced laboratory automation technology for cell-based and whole organism (e.g., microbial, worm and zebrafish) assays. This platform facilitates the automation of most steps involved in high-throughput screening of small molecule or genomic (e.g., RNAi, CRISPR) libraries. These steps include mixing reagents with cells or whole organisms, sample incubation in controlled environments, and high-content imaging at multiple levels of magnification in both bright-field and multi-channel fluorescence modes

Equipment List

●     Agilent Bravo Automated Liquid Handling Platform 

●     High-throughput Screen System

●     Honeybee Crystallization Robot

●     Microplate Dispenser