Publications

  • Highlighted Journal Articles

    Chu J, Loughlin EA, Gaur NA, Senbanerjee S, Jacob V, Monson C, Kent B, Oranu A, Ding Y, Ukomadu C, et al. 2012. UHRF1 phosphorylation by cyclin A2/cyclin-dependent kinase 2 is required for zebrafish embryogenesis. Mol Biol Cell. Jan;23:59-70. Epub 2011/11/11.

    Tsedensodnom O, Vacaru AM, Howarth DL, Yin C, Sadler KC. 2013. Ethanol metabolism and oxidative stress are required for unfolded protein response activation and steatosis in alcoholic liver disease. Dis Model Mech. Jun 27; 6:1213-1226. Epub 2013/06/27.

    Howarth DL, Lindtner C, Vacaru AM, Sachidanandam R, Tsedensodnom O, Vasilkova T, Buettner C, Sadler KC. 2014. Activating transcription factor 6 is necessary and sufficient for alcoholic Fatty liver disease in zebrafish. PLoS Genet. May;10:e1004335. Epub 2014/05/31.

    Mudbhary R, Hoshida Y, Chernyavskaya Y, Jacob V, Villanueva A, Fiel MI, Chen X, Kojima K, Thung S, Bronson RT, et al. 2014. UHRF1 overexpression drives DNA hypomethylation and hepatocellular carcinoma. Cancer Cell. Feb 10;25:196-209.

    Vacaru AM, Di Narzo AF, Howarth DL, Tsedensodnom O, Imrie D, Cinaroglu A, Amin S, Hao K, Sadler KC. 2014. Molecularly defined unfolded protein response subclasses have distinct correlations with fatty liver disease in zebrafish. Dis Model Mech. Jul;7:823-835. Epub 2014/06/29.

    Jacob V, Chernyavskaya Y, Chen X, Tan PS, Kent B, Hoshida Y, Sadler KC. 2015. DNA hypomethylation induces a DNA replication-associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryos. Development. Feb 1;142:510-521. Epub 2015/01/08.

    Bambino K, Zhang C, Austin C, Amarasiriwardena C, Arora M, Chu J, Sadler KC. 2017. Inorganic arsenic causes fatty liver and interacts with ethanol to cause alcoholic liver disease in zebrafish. Dis Model Mech. Dec 28. Epub 2018/01/24.

    Chernyavskaya Y, Mudbhary R, Zhang C, Tokarz D, Jacob V, Gopinath S, Sun X, Wang S, Magnani E, Madakashira BP, et al. 2017. Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling. Development. Aug 15;144:2925-2939. Epub 2017/07/13.

  • Review Articles

    Imrie D, Sadler KC. 2012. Stress Management: How the Unfolded Protein Response Impacts Fatty Liver Disease. J Hepatol. Jun 22;57 1147-1151. Epub 2012/06/27.

    Vacaru AM, Unlu G, Spitzner M, Mione M, Knapik EW, Sadler KC. 2014. In vivo cell biology in zebrafish - providing insights into vertebrate development and disease. J Cell Sci. Feb 1;127:485-495. Epub 2014/02/01.

    Goessling W, Sadler KC. 2015. Zebrafish: An Important Tool for Liver Disease Research. Gastroenterology. Nov;149:1361-1377.

    Madakashira BP, Sadler KC. 2017. DNA Methylation, Nuclear Organization, and Cancer. Front Genet.8:76. Epub 2017/06/24.

  • Book Chapters

    Chernyavskaya Y, Kent B, Sadler KC. 2016. Zebrafish Discoveries in Cancer Epigenetics In: Cancer and Zebrafish. Springer. p. 169-197.

    Wang S, Miller SR, Ober EA, Sadler KC. 2017. Making It New Again: Insight Into Liver Development, Regeneration, and Disease From Zebrafish Research. Curr Top Dev Biol.124:161-195.