Charlene Chen
Research Assistant
Affiliation: NYU Abu Dhabi
Education: BSc Biology New York University Abu Dhabi
Research Websites: Sadler Edepli Lab
Research Areas: Liver cancer, senescence-mediated immune surveillance, zebrafish
Charlene Chen joined as a Research Assistant after completing her undergraduate thesis at the Sadler lab. Her work builds upon a zebrafish model of oncogene-induced senescence, where overexpression of the UHRF1 oncogene induces hepatocyte senescence and later, hepatocellular carcinoma. To decipher the role of the innate immune system in this progression from liver senescence to liver cancer, Chen utilizes long-term in vivo confocal imaging, as well as molecular and sequencing techniques.