A new study by the Sadler Lab has established a link between arsenic exposure and fatty liver disease in zebrafish.
A new study by the Sadler Lab has established a link between arsenic exposure and fatty liver disease in zebrafish.
Kirsten Sadler Edepli, associate professor of biology, says NYU Abu Dhabi's "beautiful genomics center" is vital to the promising liver research projects she will be pursuing on campus.
Kirsten Sadler discusses various scientific and societal challenges, from working with a non-model organism in her lab to life as a female scientist in a Muslim country.
April 14, 2019, Professor Kirsten Sadler Edepli, gave an invited talk on“Epigenetics, cancer, and regeneration: Insight from zebrafish” at the Qatar International Zebrafish Workshop, Qatar University.
April 8-11, 2019, Professor Kirsten Sadler Edepli, gave an invited talk at the ‘Genes and Cancer’ meeting held in Robinson College, University of Cambridge, UK.
In February 4, 2019, Dr. Elena Magnani won the best poster award for her poster titled ‘ UHRF1 modifies the epigenetic landscape in senescent cells’ in the Genomics & Systems Biology IX Conference (CGSB), NYUAD, Abu Dhabi, UAE.
In February 4, 2019, Dr. Anjana Ramdas Nair, Patrice Delaney, and Dr. Soja Soman presented a poster entitled ‘Decoding the subclasses of the Unfolded Protein Response by Image-omics’ at Genomics & Systems Biology IX Conference (CGSB), NYUAD, Abu Dhabi, UAE.
In February 4, 2019, Dr. Filippo Macchi, presented a poster tilted ‘ Epigenetic Regulation in the Octopus Arm: Homoeostasis and Regeneration in the Genomics & Systems Biology IX Conference (CGSB), NYUAD, Abu Dhabi, UAE.
In February 23, 2019, Dr. Soja Soman delivered an invited talk on ‘Immune response against avian influenza and influenza vaccines at the GSG Avian Medicine Symposium, Dubai, UAE.
In November 2018, Dr. Filippo Macchi, presented a poster tilted ‘Epigenetic alteration induced by UHRF1 overexpression causes liver cancer in zebrafish‘ at the NYUAD Research Conference 2018, Abu Dhabi, UAE.
In November, Dr. Soja Soman presented a poster on ‘ Molecular immunity is modulated, while CMI appears unresponsive during unfolded protein response’ at the NYUAD Research Conference 2018, Abu Dhabi, UAE.
In November 2018, Dr. Bhavani Madakashira presented a poster ‘DNA hypomethylation in uhrf1 Deficient Zebrafish Hepatocytes result in smaller livers, defects in cell cycle progression and nuclear organization’ at EMBL Heidelberg, Germany.
In October 2018, Anjana Ramdas Nair attended and presented a poster entitled’ Structural changes to hepatocyte endoplasmic reticulum morphology predicts severity of UPR activation and progression to fatty liver disease in zebrafish at EMBO-ER workshop "Endoplasmic Reticulum in Health and Disease".October 15-18, 2018: Elena Magnani attended a workshop at the EBI-EMBL on Bioinformatics & Functional Genomics in Zebrafish.
In September 2018, Dr. Filippo Macchi, presented a paper entitled ‘ In UHRF1 overexpressing livers, where do the tumor-causing cells originate from?, NYUAD Bioforum series 2018, Abu Dhabi, UAE
September 8-16, 2018: Dr. Bhavani Madakashira attended ATAC-Seq training EMBL, Heidelberg. ATAC-Seq stands for Assay of Transposase Accessible Chromatin and is, despite its recent invention, already a widespread method to profile open chromatin on a genome-scale. — More information
August 1, 2018: Tina Kim joined as a Research Technician in the Sadler lab zebrafish facility. Tina completed her undergraduate studies in biology at NYUAD. She is managing the zebrafish facility as well as studying the epigenetic aspects of hepatocellular carcinoma using zebrafish as a model organism.
August 1, 2018: Shashi Ranjan Joined as a Research technician in the Sadler lab zebrafish facility. Shashi completed his Bachelor of Technology in Biotechnology at IASE University, Rajasthan, India and served as a zebrafish facility manager at CSIR- Institute of Genomics and Integrative Biology, New Delhi and SANSIRITI Foundation- Daulat Ram College, Delhi University, India.
August, 2018: Patrice Marie Delany joined as a graduate student in Sadler Lab. Patrice will focus on elucidating the role of unfolded protein response in the fatty liver diseases.
In July, 2018, Patrice Delaney presented a poster ‘Multi-model screens to identify the mechanism of arsenic induced toxicity’ at ZDM11 meeting, Leiden, Netherlands.
July 9-14, 2018: Dr. Bhavani Madakashira, Dr. Filippo and Patrice Marie Delany participated and presented posters in the ZDM 2018 - 11th Annual Zebrafish Disease models meeting, Leiden, The Netherlands.
June 10-15, 2018: Professor Kirsten Sadler Edepli, organized the FASEB meeting: Fundamental Biology and Pathophysiology of the Liver held at Scottsdale Plaza Resort, Arizona, USA, along with Professor David D. Moore, Baylor College of Medicine and Tom Luedde, University Hospital RWTH Aachen.
June 10-15, 2018: Dr. Soja Saghar Soman and Dr. Sammi Wang participated in FASEB meeting: Fundamental Biology and Pathophysiology of the Liver held at Scottsdale Plaza Resort, Arizona, USA. Dr. Soja has presented her research work in a poster entitled "The unfolded protein response intersects with the immune response in zebrafish with fatty liver disease." Dr Sammi presented a poster and bagged an award for her talk on "Epigenetics compensation promotes liver regeneration."
April 30-May1, 2018: Professor Kirsten Sadler Edepli organized a two-day symposium at NYUAD on "The STEM Gender Gap: Causes, Consequences and Solutions for Academia." The symposium brought together experts from across the globe who study the impact of diversity on innovation and discovery, who have identified the underlying causes of the STEM gender gap, and who have implemented effective programs to address this.
April 11-12, 2018: Sadler lab conducted their annual lab retreat at The St. Regis, Corniche, the Umm-El-Emarat Park, and Louvre Abu Dhabi. We did brain-storming on new developments in science, discussed on the Sadler lab core values, team goals, and career development.
March 25, 2018: Professor Didier Stainier visited NYUAD and interacted with Sadler lab members. Professor Didier Stainier is a prominent developmental geneticist and the Director of Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany. — More information
In February 2018, Dr. Filippo Macchi, presented a poster entitled ‘ Epigenetic reprogramming induced by UHRF1 overexpression causes senescence and liver cancer in zebrafish’ at Keystone Symposia, 2018, Breckenridge, (CO) USA.
January 20 – 26, 2018: Professor Kirsten Sadler Edepli attended and presented a poster in the keystone symposium on DNA and RNA methylation at Fairmont Hotel Vancouver, British Columbia, Canada. — More information
August 2017: A new research article was published by Yelena Chernyavskaya et al., titled Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling in the journal Development. Congratulations Yelena!
August 5-8, 2017: Dr. Anjana Ramdas Nair attended and presented a poster entitled "Two Sides of the Response to ER Stress: To Adapt or To Fail?" in the ZDM10 Annual Conference held in San Diego, CA.
August 5-8, 2017: Dr. Elena Magnani attended and presented a poster entitled "UHRF1 Overexpression in Zebrafish Embryos Induces a Novel Type of Senescence "in the ZDM10 Annual Conference held in San Diego, CA.
July 28, 2017: Dr. Kirsten Sadler Edepli delivered a talk on "Arsenic and Ethanol, a potent cocktail that elicits fatty liver disease in zebrafish" in the Toxicology Round Table at the Woods Hole Oceanographic Institute.
June 27-28, 2017: Dr. Soja Saghar Soman participated in the International Workshop 2017 — Genome Engineering in Zebrafish, held at Max Planck Institute for Brain Research, Frankfurt, Germany. The workshop focused on how to streamline CRISPR/Cas9 technology to enable knock-out, knock-in and homologous recombination events in zebrafish.
June 2017: Frontiers in Genetics published a mini-article by Bhavani Madakashira and Kirsten Sadler titled "DNA Methylation, Nuclear Organization, and Cancer."
May 3, 2017: Dr. Kirsten Sadler Edepli delivered a talk entitled "Research using little fish for solving big health problems" at the NYUAD Campus, Conference Center.
March 31, 2017: Dr. Kirsten Sadler Edepli joined the Elsevier report symposium on "Gender in the Global Research Landscape" in Washington, DC. The report covers 20 years, 12 geographies, and 27 subject areas, providing powerful insight and guidance on gender research and gender equality policy for governments, funders, and institutions worldwide. Find more details on the symposium website.
March 20-21, 2017: A workshop entitled "Making Strides in Cancer Research Using Zebrafish" was convened jointly by Dr. Kirsten Sadler Edepli, PhD Associate Professor of Biology and Richard White MD, PhD Memorial Sloan Kettering Cancer Center. The workshop was hosted by NYUAD Abu Dhabi.
January 2017: Dr. Kathryn Bambino a postdoc in the group of Dr. Kirsten Sadler at Icahn School of Medicine Mount Sinai gave a conference talk at 8th Aquatic Animal Models of Human Disease in Birmingham, Alabama, US. The title of the talk was "Arsenic enhances alcoholic liver disease in zebrafish."
January 13, 2017: Dr. Kirsten Sadler Edepli delivered a talk at the Emory University School of medicine entitled "Arsenic and Ethanol: A lethal cocktail."
January 2, 2017: Dr. Soja Saghar Soman joins the Sadler lab as a Research Scientist. Dr Soja was previously working as a Scientist-Biotechnology at The Department of President’s Affairs (DOPA), Al Ain, UAE.
November 2, 2016: The Sadler Lab held its annual lab retreat. In addition to excellent scientific discussions, we discussed our lab core values, career development, and goals. We also took time to go for a kayaking tour in the Mangroves and concluded the day with a dinner at The Ritz Carlton in Abu Dhabi.
October 30, 2016: Sammi Wang, postdoctoral researcher from NYU, joins the Sadler team in Abu Dhabi as a visiting researcher.
October 4-7, 2016: Dr. Kirsten Sadler Edepli, Bhavani Madakashira, and Elena Magnani attended the 9th Zebrafish Disease model conference in Singapore. Dr. Sadler was invited to give a talk, Bhavani was selected to present a poster and a flash talk, and Elena presented a poster.
September 2016: Undergraduate students Spencer Corbett Smith, Leonore Wunsche, Priyanka Lakhiani, Imtiyaz Haryani, and Chanyoing Kim join the lab to work on their respective projects. Fillipo Macchi, doctoral student from Italy, joins the lab at NYUAD to conduct a collaborative project, to fulfill a part of his doctoral thesis.
June 2016: Frontiers in Genetics published a new paper by Chi Zhang et al. "Comparative epigenomic profiling of the DNA methylome in mouse and zebrafish uncovers high interspecies divergence."
June 5, 2016: Chi Zhang, postdoctoral associate in the Sadler Edepli lab at Mount Sinai School of Medicine, relocated to NYUAD.
May 2, 2016: Anjana Ramdas Nair joined the lab as a postdoctoral associate.
April 2016: Developmental Biology published a new paper by Kent, et al, 2016. "UHRF1 regulation of Dnmt1 is required for pre-gastrula zebrafish development."
April 3, 2016: Elena Magnani, postdoc, relocates from NY to NYUAD to join Dr. Sadler team.
February 23-25, 2016: Genomics and Systems Biology VI Conference was held at NYUAD.
February 2016: Dr. Kirsten Sadler Edepli relocates to NYU Abu Dhabi from New York.
January 3, 2016: Maheshwar Reddy Gummala joins the lab as a postdoctoral associate.
December 13, 2015: Bhavani Madakashira Pranesh joins the lab as a postdoctoral associate.
October 5, 2015: Yelena Chernyavskaya a postdoctoral associate in the lab of Dr. Sadler relocates to NYUAD from Mount Sinai School of Medicine, New York, US.
June 1, 2015: Patrick Bradley, Zebrafish Facility manager relocates to NYUAD from Mount Sinai School of Medicine, New York, US, to establish and oversee the new Zebrafish facility.