• Selected Publications


    Xie X, Liu P-S, Percipalle P* (2018) "Analysis of global transcriptome changes in mouse embryonic fibroblasts after dsDNA and dsRNA viral mimic stimulation." Front. Immunol. - Molecular Innate Immunity, 17 April 2019.

    Percipalle P*, Vartiainen, MK (2019) "Cytoskeletal proteins in the cell nucleus: a special nuclear actin perspective." Mol Biol Cell, in press.

    Prakash V, Feenstra J, Carson B, Dass R, Sekyrova P, Hoshino A, Petersen J, Parks M, Guo Y, Haller K, Hashimoto A, Rundqvist H, Condeelis J, Allis CD, Drygin D, Nieto MA, Andäng M, Percipalle P, Bergh J, Adameyko I, Östlund Farrants A-K, Hartman J, Lyden D, Pietras K, Blanchard S, Vincent TC (2019) "De novo ribosomal RNA synthesis fuels EMT in development and disease." Nat Commun, in press.


    Neriec N, Percipalle P (2018) "Sorting mRNA molecules for cytoplasmic transport and localization." Front Genet 9: 510.

    Xie X, Venit T, Drou N, Percipalle P* (2018) "In mitochondria β-actin regulates mtDNA transcription and is required for mitochondrial quality control." iScience (Cell Press) 3: 226-237.

    Xie X, Jankauskas R, Drou N, Percipalle P* (2018) "β-actin regulates a heterochromatin landscape essential for optimal induction of neuronal programs during direct reprograming." PLoS Genet 14(12): e1007846.

    Xie X, Almuzzaini B, Drou N, Kremb S, Yousif A, Farrants AÖ, Gunsalus K, Percipalle P. (2018) "β-Actin-dependent global chromatin organization and gene expression programs control cellular identity." FASEB J. 2018 Mar; 32(3): 1296-1314.


    Almuzzaini, Bader, Aishe A. Sarshad, Aldwin S. Rahmanto, Magnus L. Hansson, Anne Von Euler, Olle Sangfelt, Neus Visa, Ann-Kristin Östlund Farrants, and Piergiorgio Percipalle. "In β-actin knockouts, epigenetic reprogramming and rDNA transcription inactivation lead to growth and proliferation defects." The FASEB Journal 30, no. 8 (2016): 2860-2873.


    Almuzzaini, Bader, Aishe A. Sarshad, Ann-Kristin Östlund Farrants, and Piergiorgio Percipalle. "Nuclear myosin 1 contributes to a chromatin landscape compatible with RNA polymerase II transcription activation." BMC biology 13, no. 1 (2015): 35.


    Sarshad AA, Corcoran M, Al-Muzzaini B, Borgonovo-Brandter L, Von Euler A, Lamont D, Visa N, Percipalle P*. (2014) "Glycogen synthase kinase (GSK) 3 β phosphorylates and protects nuclear myosin 1c from proteasome-mediated degradation to activate rDNA transcription in early G1 cells." PLoS Genet 10(6): e1004390. doi:10.1371/journal.pgen.1004390


    Sarshad A, Sadeghifar F, Louvet E, Mori R, Böhm S, Vintermist A, Fomproix N, Östlund A-K, Percipalle P* (2013) "Nuclear myosin 1 facilitates chromatin modifications required to activate rRNA gene transcription and cell cycle progression." PLoS Genetics 9: e1003397

    Fukuda N, Fukuda T, Sinnamon J, Hernandez-Hernandez A, Izadi M, Raju CS, Czaplinski K, Percipalle P. (2013) "The transacting factor CBF-A/Hnrnpab binds to the A2RE/RTS element of protamine 2 mRNA and contributes to its translational regulation during mouse spermatogenesis." PLoS Genet. 2013;9(10):e1003858. doi: 10.1371/journal.pgen.1003858. Epub 2013 Oct 17.


    Raju CS, Fukuda N, López-Iglesias C, Göritz C, Visa N, Percipalle P. (2011) "In neurons, activity-dependent association of dendritically transported mRNA transcripts with the transacting factor CBF-A is mediated by A2RE/RTS elements." Mol Biol Cell. 2011 Jun 1;22(11):1864-77. doi: 10.1091/mbc.E10-11-0904. Epub 2011 Apr 6.


    Visa N, Percipalle P. (2010) "Nuclear functions of actin." Cold Spring Harb Perspect Biol. 2010 Apr;2(4):a000620. doi: 10.1101/cshperspect.a000620. Epub 2010 Mar 17.


    Raju CS, Göritz C, Nord Y, Hermanson O, López-Iglesias C, Visa N, Castelo-Branco G, Percipalle P. (2008). "In cultured oligodendrocytes the A/B-type hnRNP CBF-A accompanies MBP mRNA bound to mRNA trafficking sequences." Mol Biol Cell. 2008 Jul;19(7):3008-19. doi: 10.1091/mbc.E07-10-1083.


    Percipalle P, Fomproix N, Cavellan E, Voit R, Reimer G, Krüger T, Thyberg J, Scheer U, Grummt I, Östlund Farrants A-K (2006) "The chromatin remodelling complex WSTF-SNF2h interacts with nuclear myosin 1and serves a role in RNA polymerase I transcription." EMBO Reports 7: 525-530


    Kukalev A, Nord Y, Palmberg C, Bergman T, Percipalle P (2005) "Actin and hnRNP U cooperate for productive transcription by RNA polymerase II." Nature Struct Mol Biol 12: 238-244.


    Fomproix N, Percipalle P. (2004) "An actin-myosin complex on actively transcribing genes." Exp Cell Res. 2004 Mar 10;294(1):140-8.


    Percipalle P, Fomproix N, Kylberg K, Miralles F, Björkroth B, Daneholt B, Visa N. (2003). "An actin–ribonucleoprotein interaction is involved in transcription by RNA polymerase II." Proc Natl Acad Sci U S A. 100: 6475–6480.


    Percipalle P, Zhao J, Pope B, Weeds A, Lindberg U, Daneholt B. (2001). "Actin Bound to the Heterogeneous Nuclear Ribonucleoprotein Hrp36 Is Associated with Balbiani Ring mRNA from the Gene to Polysomes." J Cell Biol 153: 229–236.