NMR Group
Headed by Rino Esposito, the research activity of the NMR Group of NYUAD has focused on the application of high-resolution NMR methods to proteins. This research activity is still pursued through collaborations with other NYUAD groups. Since November 2021, the main commitment of the NMR Group has been the metabolomic investigation program of the Piano Lab.
The main projects are:
- NMR metabolomics of C. elegans (Caenorhabditis elegans)
- HR-MAS NMR in vivo metabolomics of C. elegans
- Nanobodies: structural aspects and functional applications
- NMR studies of p53 DNA-binding domain
- Amyloidogenic protein interactors
- PENELOP
- BLUU-Tramp
Since 2023, the NMR group's activity has been complemented by mass spectrometry (MS) activity. A further research project has been added:
MS metabolomics of C. elegans
Collaborations
NYUAD
- Piergiorgio Percipalle (nanobodies and in vivo metabolomics)
- Mazin Magzoub (p53 DNA-binding domain; C. elegans models of amyloidosis)
- Jeremy Teo (metabolomics and lipidomics)
- Ali Trabolsi (supramolecular interactions characterization, MRI contrast agents)
- Thirumurugan Prakasam (synthesis of bioactive compound derivatives)
- Youssef Idaghdour (metabolomics)
External
- Federico Fogolari (Udine University, Udine, Italy) — modeling and molecular dynamics calculations
- József Kardos, (Eötvös Loránd University, Budapest, Hungary) — protein biophysics