Laboratory of Cell and Molecular Biology

Cell Identity, Nuclear Architecture & Metabolic Reprogramming: 
How nuclear organization encodes cell identity and metabolic state

Overview

Cell identity is governed by the spatial and functional organization of the genome within the nucleus. Our lab investigates how chromatin architecture, epigenetic regulation, and nuclear mechanics collectively determine gene expression and cellular function.

We are particularly interested in how perturbations of these systems reconfigure transcriptional and metabolic programs, contributing to the onset of cancer, metabolic disease and neurodevelopmental disorders.

Opportunities and Contact

We welcome inquiries from prospective students and postdoctoral researchers with interests in chromatin biology, nucelar organization and metabolism.

Contact: Piergiorgio Percipalle | pp69@nyu.edu