Human cells manufacture thousands of different proteins such as insulin, growth factors, and antibodies which are encapsulated into membrane-enclosed packets called vesicles. Vesicles buzz around in the cell to many different destinations in dense traffic patterns rivaling Abu Dhabi's busiest roads. Some are delivered to the cell perimeter where they discharge their contents to the exterior in an export mechanism conserved over a billion years of evolution. This lecture explores the mechanics of this process, how it is regulated, and how we can exploit this ancient biological manufacturing and transportation system for the sake of modern medicine.
Simultaneous Arabic interpretation will be provided.
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