Light Microscopy
The Light Microscopy Core Technology Platform provides access to several state-of-the-art microscopes and aids in the following research activities:
Confocal and Super-resolution Imaging
The microscopy facility applications include molecular motor transport studies, 3D neuronal network imaging and nanoparticle testing, and cell screening. The facility also can perform imaging of fluorescently labeled samples including drosophila brains, mouse brain sections, and cultured cells.
Widefield Microscopy
Various imaging techniques are used in widefield microscopy which includes epifluorescence, phase contract, and differential contrast microscopy. These are used in the core facility in various projects such as cell growth and proliferation regulation studies, actin reprogramming, and C. elegans embryogenesis.
Sample Preparation
The facility supports researchers in experimental design and suggests different labeling techniques and microscopes setups for the various applications.
Data Analysis
Various software programs are available for the post-processing of the images on a processing workstation (Autoquant, Imaris, Matlab, LasX offline license).
Equipment List
- Andor Dragonfly 600 Spinning Disk Confocal Microscope
- Biotek Instrument- LionHeart LLX
- Confocal Microscope - Leica SP8
- Confocal Microscope - Leica Stellaris 8
- Confocal Microscope - Zeiss LSM 710
- Kibero easySAM Acoustic and Photoacoustic Microscope
- Holographic Microscope - Nanolive 3D Cell Explorer
- Metallurgical Microscope - Nikon LV 100
- Optical Coherence Tomography Microscope - Thorlab Ganymede GAN611
- Stereo Microscope - Leica M165
- Super Resolution Microscope - Leica STED 3X
- Two-Photon Microscope (Upright) -Evident FV4000 MPE
- UV optimized Confocal System - Picoquant MicroTime 100 with 355 and 405 nm Lasers
- Widefield Fluorescence Microscope - Nikon Eclipse TI2
- Widefield Microscope - Leica DMI6000