The Spectrometry and Spectroscopy Core Technology Platform assists researchers in the following applications:
This facility maintains and operates a wide range of tools for separation and characterization of compounds which aids in the synthesis and discovery of chemical compounds. This core facility has a general use Q-TOF and 500 MHz NMR that synthetic chemists use for compound characterization and identification. This facility is equipped with an FT-IR, UV-VIS-NIR, and fluorescence for photophysical analysis and HPLCs to aid in precision separation. The platform offers a broad array of equipment that facilitates the synthesis and isolation of chemical compounds. Furthermore, this core is equipped with a higher field 600 MHz NMR including a cryoprobe and the first wide bore solid state 600 MHz NMR spectrometer.
Metabolomics is a term used for the characterizing and understanding of all metabolites present in living organisms. The metabolome can help us understand biochemical processes, diseases, and biodiversity by using spectroscopic and spectrometric techniques to characterize and quantify complex biological mixtures. The primary piece of equipment for this purpose is the Agilent Q-TOF 6548, but the facility is in the process of expanding the mass spectrometry facilities to better serve our research applications.
As proteins are large molecules, the same spectroscopic techniques can be used to characterize and validate these compounds, only with additional time, care, and data handling. The 600 MHz NMR with cryoprobe is mostly dedicated to understand the dynamic structure proteins in solutions.