• Journals

    Deodato, D.; Asad, N.; Dore, T. M. Photoactivatable AMPA for the Study of Glutamatergic Neuronal Transmission Using Two-Photon Excitation. Org. Biomol. Chem. 2021, 19, 5589-5594.

    Deodato, D.; Dore,. T. M. Practical Synthesis of Quinoline-Protected Morpholino Oligomers for Light-Triggered Regulation of Gene Function. Molecules 2020, 25, 2078.

    Hennig, A.-L. K.; Deodato, D.; Asad, N.; Herbivo, C.; Dore, T. M. Two-Photon Excitable Photoremovable Protecting Groups Based on the Quinoline Scaffold for Use in Biology. J. Org. Chem. 2020, 85, 726-744.

    Deodato, D.; Asad, N.; Dore, T. M. Photorearrangement of Quinoline-Protected Dialkylanilines and the Photorelease of Aniline-Containing Biological Effectors. J. Org. Chem. 2019, 84, 7342-7353.

    O'Connor, M. J.; Beebe, L. L.; Deodato, D.; Ball, R. E.; Page, A. T.; VanLeuven, A. J.; Harris, K. T.; Park, S.; Hariharan, V.; Lauderdale, J. D.; Dore, T. M. Bypassing Glutamic Acid Decarboxylase 1 (Gad1) Induced Craniofacial Defects with a Photoactivatable Translation Blocker Morpholino. ACS Chem. Neurosci. 2019, 10, 266-278.

    Pasero, C.; Dagostino, I.; De Luca, F.; Zamperini, C.; Deodato, D.; Truglio, G. I.; Sannio, F.; Del Prete, R.; Ferraro, T.; Visaggio, D.; Mancini, A.; Guglielmi, M. B.; Visca, P.; Docquier, J.-D.; Botta, M. Alkyl-guanidine compounds as potent broad-spectrum antibacterial agents: Chemical library extension and biological characterization. J. Med. Chem. 2018, 61, 9162-9176.

    D'Agostino, I.; Giacchello, I.; Nannetti, G.; Fallacara, A. L.; Deodato, D.; Musumeci, F.; Grossi, G.; Palu, G.; Cau, Y.; Trist, I. M.; Loregian, A.; Schenone, S.; Botta, M. Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction. Eur. J. Med. Chem. 2018, 157, 743-758.

    Mori, M.; Deodato, D.; Kasula, M.; Ferraris, D. M.; Sanna, A.; De Logu, A.; Rizzi, M.; Botta, M. Design, synthesis, SAR and biological investigation of 3-(carboxymethyl)rhodanine and aminothiazole inhibitors of Mycobacterium tuberculosis Zmp1. Bioorg. Med. Chem. Lett. 2018, 28, 637-641.

    Asad, N.; Deodato, D.; Lan, X.; Widegren, M. B.; Phillips, D. L.; Du, L.; Dore, T. M. Photochemical Activation of Tertiary Amines for Applications in Studying Cell Physiology. J. Am. Chem. Soc. 2017, 139, 12591-12600.

    Huang, J.; Muliawan, A. P.; Ma, J.; Li, M. D.; Chiu, H. K.; Lan, X.; Deodato, D.; Phillips, D. L.; Dore, T. M. A Spectroscopic Study of the Excited State Proton Transfer Processes of (8-Bromo- 7-hydroxyquinolin-2-yl)methyl-Protected Phenol in Aqueous Solutions. Photochem. Photobiol. Sci. 2017, 16, 575-584.

    Zamperini, C.; Maccari, G.; Deodato, D.; Pasero, C.; D'Agostino, I.; Orofino, F.; De Luca, F.; Dreassi, E.; Docquier, J.D.; Botta, M. Identification, Synthesis and Biological Activity of Alkyl-Guanidine Oligomers as Potent Antibacterial Agents. Sci. Rep. 2017, 7, 8251.

    Maccari, G.; Deodato, D.; Fiorucci, D.; Orofino, F.; Truglio, G. I.; Pasero, C.; Martini, R.; De Luca, F.; Docquier, J.-D.; Botta, M. Design and Synthesis of a Novel Inhibitor of T. viride Chitinase Through an in Silico Target Fishing Protocol. Bioorg. Med. Chem. Lett. 2017, 27, 3332-3336.

    Deodato, D.; Maccari, G.; De Luca, F.; Sanfilippo, S.; Casian, A.; Martini, R.; D'Arezzo, S.; Bonchi, C.; Bugli, F.; Posteraro, B.; Vandeputte, P.; Sanglard, D.; Docquier, J.-D.; Sanguinetti, M.; Visca, P.; Botta, M. Biological Characterization and in Vivo Assessment of the Activity of a New Synthetic Macrocyclic Antifungal Compound. J. Med. Chem. 2016, 59, 3854-3866.

    Tintori, C.; Brai, A.; Dasso Lang, M. C.; Deodato, D.; Greco, A. M.; Bizzarri, B. M.; Cascone, L.; Casian, A.; Zamperini, C.; Dreassi, E.; Crespan, E.; Maga, G.; Vanham, G.; Ceresola, E.; Canducci, F.; Arien, K. K.; Botta, M. Development and in Vitro Evaluation of a Microbicide Gel Formulation for a Novel Non-Nucleoside Reverse Transcriptase Inhibitor Belonging to the N-Dihydroalkyloxybenzyloxopyrimidines (N-DABOs) Family. J. Med. Chem. 2016, 59, 2747-2759.

    Trist, I. M. L.; Nannetti, G.; Tintori, C.; Fallacara, A. L.; Deodato, D.; Mercorelli, B.; Palu, G.; Wijtmans, M.; Gospodova, T.; Edink, E.; Verheij, M.; de Esch, I.; Viteva, L.; Loregian, A.; Botta, M. 4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling. J. Med. Chem. 2016, 59, 2688-2703.

    Pagano, M.; Castagnolo, D.; Bernardini, M.; Fallacara, A. L.; Laurenzana, I.; Deodato, D.; Kessler, U.; Pilger, B.; Stergiou, L.; Strunze, S.; Tintori, C.; Botta, M. The Fight against the Influenza A Virus H1N1: Synthesis, Molecular Modeling, and Biological Evaluation of Benzofurazan Derivatives as Viral RNA Polymerase Inhibitors. ChemMedChem 2014, 9, 129-150.

    Maccari, G.; Sanfilippo, S.; De Luca, F.; Deodato, D.; Casian, A.; Dasso Lang, M. C.; Zamperini, C.; Dreassi, E.; Rossolini, G. M.; Docquier, J.-D.; Botta, M. Synthesis of Linear and Cyclic Guazatine Derivatives Endowed with Antibacterial Activity. Bioorg. Med. Chem. Lett. 2014, 24, 5525-5529.

    Mori, M.; Moraca, F.; Deodato, D.; Ferraris, D. M.; Selchow, P.; Sander, P.; Rizzi, M.; Botta, M. Discovery of the First Potent and Selective Mycobacterium tuberculosis Zmp1 Inhibitor. Bioorg. Med. Chem. Lett. 2014, 24, 2508-2511.

    Kessler, U.; Castagnolo, D.; Pagano, M.; Deodato, D.; Bernardini, M.; Pilger, B.; Ranadheera, C.; Botta, M. Discovery and Synthesis of Novel Benzofurazan Derivatives as Inhibitors of Influenza A Virus. Bioorg. Med. Chem. Lett. 2013, 23, 5575-5577.