Latest News from the Biology Program

Researchers Unlock Secrets Behind Liver Regrowth that Could Help Inform Development of Regenerative Medicine
New insights into the liver’s unique ability to regenerate holds promise for developing treatments for the lung, heart, and other organs that currently must be replaced by transplants.

Study Finds Inhibitors of Protein Aggregation Associated with Alzheimer’s Disease Can Develop Cancer Therapies
Small molecule designed to inhibit protein aggregation associated with Alzheimer’s disease and Type II diabetes is shown to effectively reactivate a critical tumor suppressor protein inactivated in more than one-half of all human cancers

Going Viral
Nanobodies derived from the South American llama could help scientists provide a more efficient COVID-19 screening method and, potentially, a robust antiviral drug for coronavirus patients.

New Study Offers Insight into One of the Mysteries of Natural Immunity to Malaria
In the first and largest global metabolomic study of African children before and after malaria infection, researchers have advanced the understanding of the molecular mechanisms in play during human malaria and demonstrated how studying ethnic differences in metabolic responses to the infection can help explain the sources of susceptibility and resistance in this deadly disease.

New Research Shows Computer-based Modeling Can Predict Mutation “Hotspots” and Antibody Escapers in the SARS-CoV-2 Spike Protein
Study identifies structural basis of spike protein mutations with stronger binding and antibody resistance, which may explain transmissibility of new COVID-19 variants

Researchers Sequence the Genome of Extinct Date Palms Germinated From 2,000 Year-old Seeds
This study marks the first time researchers have sequenced the genomes of plants from ancient germinated seeds

Featured Research

Recent Publications

Below is a selection of recent publication highlights from the Biology Program. The full citations are not listed but can be accessed through the links.

Tight Adherence (Tad) Pilus Genes Indicate Putative Niche Differentiation in Phytoplankton Bloom Associated Rhodobacterales
Shady Amin | Frontiers in Microbiology

Unraveling the Predictive Role of Temperature in the Gut Microbiota of the Sea Urchin Echinometra sp. EZ across Spatial and Temporal Gradients

John Burt | Molecular Ecology

Neural Specification, Targeting, and Circuit Formation during Visual System Assembly
Claude Desplan | Proceedings of the National Academy of Sciences of the United States of America

The Microbiota of Healthy Dogs Demonstrates Individualized Responses to Synbiotic Supplementation in a Randomized Controlled Trial
Aashish Jha | Animal Microbiome

Nuclear Organization during Hepatogenesis in Zebrafish Requires Uhrf1
Kirsten Sadler Edepli | Nature Communications

Alternative Glycosylation Controls Endoplasmic Reticulum Dynamics and Tubular Extension in Mammalian Cells
Kourosh Salehi-Ashtiani | Science Advances

Synthesis and Evaluation of Coastal and Marine Biodiversity Spatial Information in the United Arab Emirates for Ecosystem-based Management
John Burt | Marine Pollution Bulletin

Manipulating and Tracking Single Hepatocyte Behavior during Mouse Liver Regeneration by Performing Hydrodynamic Tail Vein Injection
Kirsten Sadler Edepli | STAR Protocols

Applying the Ecosystem Services - EBM Framework to Sustainably Manage Qatar's Coral Reefs and Seagrass Beds
John Burt | Ocean & Coastal Management

Mitogenome Analyses Elucidate the Evolutionary Relationships of a Probable Eocene Wet Tropics Relic in the Xerophilic Lizard Genus Acanthodactylus
Sebastian Kirchof, Stephane Boissinot | Scientific Reports

uhrf1 and dnmt1 Loss Induces an Immune Response in Zebrafish Livers Due to Viral Mimicry by Transposable Elements
Kirsten Sadler Edepli | Frontiers in Immunology

Hovlinc is a Eecently Evolved Class of Ribozyme Found in Human lncRNA
Kourosh Salehi-Ashtiani | Nature Chemical Biology