Kirsten Sadler Edepli, Associate Professor of Biology, Science, NYUAD
Kirsten Sadler Edepli, Associate Professor of Biology, Science, NYUAD

Kirsten Sadler Edepli

Associate Professor of Biology, Science

Affiliation: NYU Abu Dhabi

e: kirsten.edepli@nyu.edu

Biography

B.A. Mount Holyoke College (Biology and Anthropology)
M. Med. Sci. Harvard Medical School
Ph.D. Harvard University
Post-doctoral training MIT

Dr. Kirsten Sadler Edepli is a basic science and translational researcher focusing on the molecular basis of liver development and two important liver diseases, liver cancer and fatty liver disease. She completed a B.A. at Mount Holyoke College in MA, a Masters in Medical Sciences at Harvard Medical School (1994) and a Ph.D. in Cell and Developmental Biology at Harvard University (1998).

She joined the faculty at Bosphorus University in Istanbul/Turkey and then moved to work with Nancy Hopkins at MIT where she screened for zebrafish mutants with liver disease and growth defects. She started her lab as assistant professor at The Icahn School of Medicine at Mount Sinai in NY in 2006, was promoted to associate professor in 2013 and joined the faculty of New York University in Abu Dhabi as a tenured associate professor in Biology in 2015. She runs an active research group, teaches and serves as the faculty advisor for Women Empowered in STEM at NYUAD.

For more informatin, please visit Kisten Sadler Edepli's Lab website.

Selected Publications

For a full list of publications, please click here.

  • Jacob, V., Chernyavskaya, Y., Chen, X., Tan, P.S., Kent, B., Hoshida, Y., and Sadler, K.C. (2015) DNA hypomethylation prevents S-phase exit and restricts organ size in uhrf1 zebrafish mutants. Development 142(3):510-21.
  • Vacaru, A.M., Di Narzo, A.F., Howarth, D.L., Tsedensodnom, O., Imrie, D., Cinaroglu, A., Amin, S., Hao, K., Sadler, K.C., 2014. Molecularly defined unfolded protein response subclasses have distinct correlations with fatty liver disease in zebrafish. Disease Models and Mechanisms. 7, 823-835. Special Issue: Spotlight on Zebrafish: Translational Impac
  • Howarth, D.L., Lindtner, C. Sachidanandam, R, Tsedensodnom, O., Vacaru, A.M., Vasilkova, T. Buettner, C. and Sadler, K.C. (2014) Activating transcription factor 6 is necessary and sufficient for fatty liver disease PLoS Genet 10(5), e1004335.
  • Mudbhary, R., Hoshida, Y., Chernyavskaya, Y., Villanova, N., Jacob, V., Fiel, I., Chen, X., Kojima, K., Thung, S., Bronson, R.T., Lachenmayer, A., Alsinet, C., Desai, A., Senbanerjee, S., Ukomadu, C., Llovet, J.M., Sadler, K.C., 2014. Overexpression of UHRF1 drives DNA hypomethylation and hepatocellular carcinoma. Cancer Cell 25, 1-14.

    Media Coverage:
    http://www.sciencedaily.com/releases/2014/01/140130121611.htm

  • Tsedensodnom, O., Vacaru, A.M., Howarth, D.L., Yin, C. & Sadler, K.C. (2013) Ethanol metabolism and oxidative stress are required for unfolded protein response activation and steatosis in alcoholic liver disease. Disease Models and Mechanisms. 6,1213-1226.
  • Goessling W and Sadler, K.C. (2015) Zebrafish: An Important Tool for Liver Disease Research. Gastroenterology. 149 (6), 1361-77