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Gennaro Esposito, Visiting Research Professor, Science, NYUAD

Gennaro Esposito

Visiting Research Professor, Science

Affiliation: NYU Abu Dhabi

Biography

Laurea in Chimica, Chemistry Institute of Naples University

Gennaro Esposito was born in Naples, Italy, where he studied and got the Laurea in Chimica cum laude in 1979. From 1980 to 1982 he was a chemistry teacher in secondary schools, and worked at the NMR spectroscopy laboratory of Naples University. From Sept. 1982 to Jan. 1990 he was researcher at the NMR laboratory of Assoreni, later renamed Eniricerche, (Monterotondo - Rome). In Feb. 1990 he moved at the University of Udine, first as a biophysics researcher and later, from Sept. 2000, as an associate professor of Applied Physics, the position he still keeps. From 2002 to 2015 he was responsible for the mass spectrometry laboratory of MATI centre. He had prolonged international work experience (Jun./Dec. 1983 and Mar. 1985/Sept. 1986 Biochemistry Dept.-Oxford University, UK; Jul./Dec. 1987 School of Pharmacy-London University, UK; Aug. 1993/Jul. 1994 Lausanne University, CH). He was invited as a visiting professor at University J. Fourier, Grenoble, F (Jul.-Aug. 2001) and at Institute for Protein Research, University of Osaka, Japan (May-Jun. 2012, June 2013).

He does research in the field of NMR spectroscopy and biopolymer biophysics. He is coauthor of over 135 publications on international peer-reviewed journals and about 300 communications in proceedings of national and international conferences. He was member of GERAMY Advisory Board (2012-15), a consortium for the study of systemic amyloidosis. He is currently in the Editorial Board of BBA (Protein and Proteomics) and ISRN Structural Biology. In 2013 he received the Gold Medal for his NMR research activity. As leading unit-responsible scientist or as national co-ordinator, he got several research grants (National Research Council – 1994, 1996, 1998; University Ministry COFIN/PRIN– 1998, 2003, 2006, 2008, 2013; University Ministry FIRB - 2003, 2007; European Union – 1998, 2006; Health Ministry – 2001).

Selected Publications

  • Raimondi S., Porcari R., Mangione P.P., Verona G., Marcoux J., Giorgetti S., Taylor G.W., Elllmerich S., Ballico M., Zanini S., Pardon E., Al-Shawi R., J.P. Simons, Corazza A., Fogolari F., Gillmore J.D., P.N. Hawkins, Valli M., Stoppini M., Robinson C.V., Steyaert J., Esposito G., Bellotti V. (2017). A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo Scientific Reports, 7: 46711; doi: 10.1038/srep46711.
  • Cantarutti C., Raimondi S., Brancolini G., Corazza A., Giorgetti S., Ballico M., Zanini S., Palmisano G., Bertoncin P., Marchese L., Mangione P.P., Bellotti V., Corni S., Fogolari F., Esposito G. (2017) Citrate-stabilized Gold Nanoparticles hinder fibrillogenesis of a pathologic variant of β2-microglobulin. Nanoscale, 9: 3941-3951.
  • Banelli T., Vuano M., Fogolari F., Fusiello A., Esposito G., Corazza A. (2017). Automation of peak-tracking analysis of stepwise perturbed NMR spectra J. Biomol. NMR, 67: 121-134.
  • Camilloni C., Sala B., Sormanni P., Porcari R., Corazza A., de Rosa M., Zanini S., Barbiroli A., Esposito G., Bolognesi M., Bellotti V., Vendruscolo M., Ricagno S. (2016). Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability Scientific Reports, 6: 25559; doi: 10.1038/srep25559.
  • Fogolari F., Dongmo Foumthium C.J, Fortuna S., Soler M.A., Corazza A., Esposito G. (2016) Accurate estimation of the entropy of the rotation-translation probability distribution. Journal of Chemical Theory and Computation, 12: 1-8.
  • Fogolari F., Corazza A., Fortuna S., Soler M.A., VanSchouwen B., Brancolini G., Corni S., Melacini G., Esposito G. (2015). Distance-Based Configurational Entropy of Proteins from Molecular Dynamics Simulations. PLoS ONE 10 (7): e0132356; doi:10.1371/journal.pone.0132356.

  • Brancolini G., Corazza A., Vuano M., Fogolari F., Mimmi M.C., Bellotti V., Stoppini M., Corni S, Esposito G. (2015). Probing the Influence of Citrate-Capped Gold Nanoparticles on an Amyloidogenic Protein. ACS Nano, 9: 2600-2613.
  • Fogolari F., Corazza A., Esposito G. (2015). Accuracy Assessment of the Linear Poison-Boltzmann Equation and Reparametrization of the OBC Generalized Born Model for Nucleic Acids and Nucleic Acid-Protein Complexes. J. Comput. Chem., 36: 585-596.
  • Baratta W. Baldino S., Calhorda M.J., Costa P.J., Esposito G., Herdtweck E., Magnolia S., Mealli C., Messaoudi A., Mason S.A., Veiros L.F. (2014). CNN Pincer Ruthenium Catalysts for Hydrogenation and Transfer Hydrogenation of Ketones: Experimental and Computational Studies. Chem. Eur. J., 20: 13603-13617.
  • Halabelian L. Ricagno S., Giorgetti S., Santambrogio C. Barbiroli A., Pellegrino S., Achour A., Grandori R. Marchese L., Raimondi S., Mangione P. P., Esposito G., Al-Shawi R., Simons J.P., Speck I., Stoppini M., Bolognesi M., Bellotti V. (2014). Class I Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic β2-Microglobulin. J. Biol. Chem. 289: 3318-3327.